Ganglioside sugars (Ganglio-Series) 神經(jīng)節(jié)苷脂糖

Ganglioside sugars (Ganglio-Series) 神經(jīng)節(jié)苷脂糖

神經(jīng)節(jié)苷脂是復(fù)雜的鞘糖脂（簡稱GSL，也被稱為糖脂），包含唾液酸。它們是脊椎動物細(xì)胞膜的建構(gòu)單元，在細(xì)胞到細(xì)胞和細(xì)胞到細(xì)胞外基質(zhì)（毒素，激素，病毒的受體……）通信時(shí)發(fā)揮關(guān)鍵作用。作為腫瘤發(fā)病機(jī)制的一部分，這些分子算是疫苗的進(jìn)攻目標(biāo)。

神經(jīng)節(jié)苷脂糖系統(tǒng)命名法:
G代表神經(jīng)節(jié)苷脂
M, D, T & Q分別代表單個(gè)，兩個(gè)，三個(gè)，四個(gè)唾液酸
1，2，3為薄層色譜中距離遷移的順序

了解更多
Modified from Essentials of Glycobiology 2nd Edition, Varki A, Cummings RD, Esko JD, et al., editors. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2009.
J. Heimburg-Molinaro et al., Vaccine 29 (2011) 8802-8826.
S. Hakomori. Biochimica etBiophysica Acta 1780 (2008) 325-346.

上海甄準(zhǔn)生物提供神經(jīng)節(jié)苷脂糖，原裝進(jìn)口，咨詢/訂購熱線：400-002-3832

產(chǎn)品編號	產(chǎn)品名稱		產(chǎn)品描述
規(guī)格: 5 mg, 25 mg, 100 mg, 1 g, 5 g
EOT-GLY090		GM3神經(jīng)節(jié)苷脂糖/ 3'-唾液酸乳糖 GM3 Ganglioside sugar 3'Sialyllactose			Neu5Acα2-3Galβ1-4Glc C23H38NO19Na FW 655.53 [35890-38-1]
		Human Milk Oligosaccharide Kunz et al., 2000. Ann Rev Nutr 20, 699-722 Product provided for the following study: “Chemoenzymatic synthesis of GM3 and GM2 gangliosides containing a truncated ceramide functionalized for glycoconjugate synthesis and solid phase applications”. Jacques S et al,. 2006. Org Biomol Chem. 2006 Jan 7;4(1):142-54
EOT-GLY091		GD3神經(jīng)節(jié)苷脂糖/ 二唾液酸乳糖 GD3 Ganglioside sugar Disialyl lactose / DS-L				Neu5Acα2-8Neu5Acα2-3Galβ1-4Glc C34H54N2O27Na2 FW 968.76
		Tumor-associated carbohydrate antigen (TACA) Birkle S et al. 2003. Biochimie. 85(3-4): 455-63 Bovine Milk & Colostrum P. K. Gopal et al. British Journal of Nutrition (2000), 84, Suppl 1, S69-S74
EOT-GLY092		GT3神經(jīng)節(jié)苷脂糖/ 三唾液酸乳糖 GT3 Ganglioside sugar Trisialyl lactose					Neu5Acα2-8Neu5Acβ2-8Neu5Acα2-3Galβ1-4Glc C45H70N3O35Na3 FW 1282.00

EOT-GLY105		GQ3神經(jīng)節(jié)苷脂糖/ 四唾液酸乳糖 GQ3 Ganglioside sugar Quadrisialyl lactose					Neu5Acα2-8Neu5Acα2-8Neu5Acβ2-8Neu5Acα2-3Galβ1-4Glc C56H86N4O43Na4 FW 1595.23

EOT-GLY093		GM2神經(jīng)節(jié)苷脂糖 GM2 Ganglioside sugar						GalNAcβ1-4(Neu5Acα2-3)Galβ1-4Glc C31H51N2O24Na FW 858.72

EOT-GLY094		GD2神經(jīng)節(jié)苷脂糖 GD2 Ganglioside sugar						GalNAcβ1-4(Neu5Acα2-8Neu5Acα2-3)Galβ1-4Glc C42H67N3O32 Na2 FW 1171.95

EOT-GLY095		GT2神經(jīng)節(jié)苷脂糖 GT2 Ganglioside sugar						GalNAcβ1-4(Neu5Acα2-8Neu5Acα2-8Neu5Acα2-3)Galβ1-4Glc C53H83N4O40 Na3 FW 1485.19

EOT-GLY096		GM1a神經(jīng)節(jié)苷脂糖 GM1a Ganglioside sugar						Galβ1-3GalNAcβ1-4(Neu5Acα2-3)Galβ1-4Glc C37H61N2O29 Na FW 1020.86 [67063-78-9]

EOT-GLY097		GM1b神經(jīng)節(jié)苷脂糖 GM1b Ganglioside sugar		Neu5Acα2-3Galβ1-3GalNAcβ1-4Galβ1-4Glc C37H61N2O29Na FW 1020.86

EOT-GLY098		GD1a神經(jīng)節(jié)苷脂糖 GD1a Ganglioside sugar	Neu5Acα2-3Galβ1-3GalNAcβ1-4(Neu5Acα2-3)Galβ1-4Glc C48H77N3O37Na2 FW 1334.09
		Functional ligands for myelin stability and the control of nerve regeneration Vyas, A et al., 2001. Biochimie. 83(7): 677-82.
EOT-GLY099		GD1b神經(jīng)節(jié)苷脂糖 GD1b Ganglioside sugar	Galβ1-3GalNAcβ1-4(Neu5Acα2-8Neu5Acα2-3)Galβ1-4Glc C48H77N3O37Na2 FW 1334.09

EOT-GLY100		GT1a神經(jīng)節(jié)苷脂糖 GT1a Ganglioside sugar	Neu5Acα2-8Neu5Acα2-3Galβ1-3GalNAcβ1-4(Neu5Acα2-3)Galβ1-4Glc C59H93N4O45Na3 FW 1647.33

EOT-GLY101		GT1c神經(jīng)節(jié)苷脂糖 GT1c Ganglioside sugar	Galβ1-3GalNAcβ1-4(Neu5Acα2-8Neu5Acα2-8Neu5Acα2-3)Galβ1-4Glc C59H93N4O4, 5Na3 FW 1647.33

EOT-GLY102		aGM1(缺唾液酸GM1)神經(jīng)節(jié)苷脂糖 / GA1 aGM1 (asialo GM1) Ganglioside sugar / GA1	Galβ1-3GalNAcβ1-4Galβ1-4Glc C26H45NO21 FW 707.62 [75645-24-8]

EOT-GLY103		巖藻糖GM1神經(jīng)節(jié)苷脂糖 Fucosyl GM1 Ganglioside sugar	Fucα1-2Galβ1-3GalNAcβ1-4(Neu5Acα2-3)Galβ1-4Glc C43H71N2O33Na FW 1168.00
		Tumor associated carbohydrate antigen expressed in small cell lung cancer (TACA), Dickler. MN et al,. Clin Cancer Res. 1999. Oct ; 5(10): 2773-9
EOT-GLY104		aGM2(缺唾液酸GM2)神經(jīng)節(jié)苷脂糖 / GA2 aGM2 (asialo GM2) Ganglioside sugar / GA2	GalNAcβ1-4Galβ1-4Glc C20H35NO16 FW 545.48