血型和Lewis抗原Blood group and Lewis antigens

Blood group and Lewis antigens 血型和Lewis抗原

組織-血型抗原又稱HBGs（A，B，H），相關(guān)抗原是存在于紅血細(xì)胞和呼吸道粘膜上皮表面，以及泌尿生殖系統(tǒng)和消化道的復(fù)雜碳水化合物。它們也以游離糖的形式存在于生物液體，如唾液、腸內(nèi)容物，人乳（HMO）和血液中。

§ 分泌型(Se): 個(gè)體口腔粘膜分泌積極而表達(dá)的ABH抗原。分泌型個(gè)體表達(dá)分泌腺-巖藻糖轉(zhuǎn)移酶FUT2產(chǎn)生H抗原。

§ 非分泌型 (Se0): 非分泌型個(gè)體缺乏分泌腺轉(zhuǎn)移酶，產(chǎn)生較短小的Lewisa抗原(Lea)。

§ 孟買型: 個(gè)體由于FUT1基因突變，缺乏循環(huán)系統(tǒng)里血紅細(xì)胞的巖藻糖型ABH抗原（稀有表型）。

進(jìn)一步閱讀
Marionneau et al. 2001. ABH and Histo-blood Group antigens. Biochimie, 83; 565?573.
Tan et al. Norovirus and its HBGA receptors: an answer to historical puzzle. Trends in microbiology, Vol.13 No.6 (2005)

上海甄準(zhǔn)生物提供組織-血型抗原低聚葡聚糖，原裝進(jìn)口，咨詢/訂購熱線：400-002-3832

產(chǎn)品編號(hào)	產(chǎn)品名稱			產(chǎn)品描述
規(guī)格: 5 mg, 25 mg, 100 mg, 1 g, 5 g
H血型抗原(血型O型) 原裝進(jìn)口，咨詢/訂購熱線：400-002-3832
EOT-GLY030		H血型抗原二糖 Blood group H antigen disaccharide				Fucα1-2Gal C12H22O10 FW 326.29 [16741-18-7] [24656-24-4] [146076-26-8]
EOT-GLY031-1		H血型抗原三糖，1型 Blood group H antigen triaose type 1				Fucα1-2Galβ1-3GlcNAc C20H35O15 FW 529.49
EOT-GLY031-2		H血型抗原三糖，2型 Blood group H antigen triaose type 2				Fucα1-2Galβ1-4GlcNAc C20H35O15 FW 529.49
EOT-GLY031-3		H血型抗原三糖，5型 2‘-巖藻乳糖/2’FL Blood group H antigen triaose type 5 2’Fucosyllactose/ 2’FL				Fucα1-2Galβ1-4Glc C18H32O15 FW 488.43 [41263-94-9]
		Human Milk Oligosaccharide Kunz et al., 2000. Ann Rev Nutr. 20, 699-722
EOT-GLY032-1		H血型抗原四糖，1型 Blood group H antigen tetraose type 1		Fucα1-2Galβ1-3GlcNAcβ1-3Gal C26H45NO20 FW 691.62
GLY032-2		H血型抗原四糖，2型 Blood group H antigen tetraose type 2		Fucα1-2Galβ1-4GlcNAcβ1-3Gal C26H45NO20 FW 691.62
EOT-GLY127		H血型抗原四糖，4型/Globo H四糖 Blood group H antigen tetraose type 4/ Globo H tetraose		Fucα1-2Galβ1-3GalNAcβ1-3Gal C26H45NO20 FW 691.62
EOT-GLY033-1		H血型抗原五糖，1型乳-N-巖藻五糖 I (LNFP I) Blood group H antigen pentaose type 1 Lacto-N-fucopentaose I (LNFP I)		Fucα1-2Galβ1-3GlcNAcβ1-3Galβ1-4Glc C32H55NO25 FW 853.76 [7578-25-8]
		Human Milk Oligosaccharide Kunz et al., 2000. Ann Rev Nutr. 20, 699-722
EOT-GLY033-2		H血型抗原五糖，2型乳-N-新巖藻五糖 I (LNFP I) Blood group H antigen pentaose type 2 Lacto-N-neofucopentaose I (LnNFP I)		Fucα1-2Galβ1-4GlcNAcβ1-3Galβ1-4Glc C32H55NO25 FW 853.76

A血型抗原原裝進(jìn)口，咨詢/訂購熱線：400-021-8158
EOT-GLY034			A血型抗原三糖 Blood group A antigen triose	GalNAcα1-3(Fucα1-2)Gal C20H35NO15 FW 529.49 [49777-13-1]
EOT-GLY035-1			A血型抗原四糖，1型 Blood group A antigen tetraose type 1	GalNAcα1-3(Fucα1-2)Galβ1-3GlcNAc C28H48N2O20 FW 732.68
EOT-GLY035-2			A血型抗原四糖，2型 Blood group A antigen tetraose type 2	GalNAcα1-3(Fucα1-2)Galβ1-4GlcNAc C28H48N2O20 FW 732.6
EOT-GLY035-3			A血型抗原四糖，5型 Blood group A antigen tetraose type 5	GalNAcα1-3(Fucα1-2)Galβ1-4Glc C26H45NO20 FW 691.62 [59957-92-5]
EOT-GLY035-4			A血型 Lewis^b抗原五糖，1型 Blood group A Lewis^b antigen pentaose type 1	GalNAcα1-3(Fucα1-2)Galβ1-3(Fucα1-4)GlcNAc C34H58N2O24 FW 878.82
EOT-GLY035-5			A血型 Lewis^Y抗原五糖，2型 Blood group A Lewis^Y antigen pentaose type 2	GalNAcα1-3(Fucα1-2)Galβ1-4(Fucα1-3)GlcNAc C34H58N2O24 FW 878.82
EOT-GLY036-1			A血型抗原五糖，1型 Blood group A antigen pentaose type 1	GalNAcα1-3(Fucα1-2)Galβ1-3GlcNAcβ1-3Gal C34H58N2O25 FW 894.82 [50624-46-9]

EOT-GLY036-2			A血型抗原五糖，2型 Blood group A antigen pentaose type 2	GalNAcα1-3(Fucα1-2)Galβ1-4GlcNAcβ1-3Gal C34H58N2O25 FW 894.82

EOT-GLY128			A血型抗原五糖，4型 Blood group A antigen pentaose type 4		GalNAcα1-3(Fucα1-2)Galβ1-3GalNAcβ1-3Gal C34H58N2O25 FW 894.82

EOT-GLY037-1			A血型抗原六糖，1型 Blood group A antigen hexaose type 1	GalNAcα1-3(Fucα1-2)Galβ1-3GlcNAcβ1-3Galβ1-4Glc C40H68N2O30 FW 1056.96

EOT-GLY037-2			A血型抗原六糖，2型 Blood group A antigen hexaose type 2	GalNAcα1-3(Fucα1-2)Galβ1-4GlcNAcβ1-3Galβ1-4Glc C40H68N2O30 FW 1056.96

B血型抗原原裝進(jìn)口，咨詢/訂購熱線：400-002-3832
EOT-GLY038-1	B血型抗原四糖，1型 Blood group B antigen tetraose type 1			Galα1-3(Fucα1-2)Galβ1-3GlcNAc C26H45NO20 FW 691.62
EOT-GLY038-2	B血型抗原四糖，2型 Blood group B antigen tetraose type 2			Galα1-3(Fucα1-2)Galβ1-4GlcNAc C26H45NO20 FW 691.62
EOT-GLY038-3	B血型抗原四糖，5型 Blood group B antigen tetraose type 5			Galα1-3(Fucα1-2)Galβ1-4Glc C24H42O20 FW 650.57
EOT-GLY038-4	B血型Lewis^b抗原五糖，1型 Blood group B Lewis^b antigen pentaose type 1			Galα1-3(Fucα1-2)Galβ1-3(Fucα1-4)GlcNAc C32H55NO24 FW 837.77
EOT-GLY038-5	B血型Lewis^b抗原五糖，1型 Blood group B Lewis^Y antigen pentaose type 2			Galα1-3(Fucα1-2)Galβ1-4(Fucα1-3)GlcNAc C32H55NO24 FW 837.77

EOT-GLY039-1	B血型抗原五糖，1型 Blood group B antigen pentaose type 1			Galα1-3(Fucα1-2)Galβ1-3GlcNAcβ1-3Gal C32H55NO25 FW 853.76

EOT-GLY039-2	B血型抗原五糖，2型 Blood group B antigen pentaose type 2			Galα1-3(Fucα1-2)Galβ1-4GlcNAcβ1-3Gal C32H55NO25 FW 853.76

EOT-GLY129	B血型抗原五糖，4型 Blood group B antigen pentaose type 4			Galα1-3(Fucα1-2)Galβ1-3GalNAcβ1-3Gal C32H55NO25 FW 853.76

EOT-GLY040-1	B血型抗原六糖，1型 Blood group B antigen hexaose type 1			Galα1-3(Fucα1-2)Galβ1-3GlcNAcβ1-3Galβ1-4Glc C38H65NO30 FW 1015.90

EOT-GLY040-2	B血型抗原六糖，2型 Blood group B antigen hexaose type 2			Galα1-3(Fucα1-2)Galβ1-4GlcNAcβ1-3Galβ1-4Glc C38H65NO30 FW 1015.90

Lewis抗原原裝進(jìn)口，咨詢/訂購熱線：400-002-3832
EOT-GLY049	Lewis^X抗原三糖 (Le^X) Lewis^X (Le^X) triaose SSEA-1 / CD15			Galβ1-4(Fucα1-3)GlcNAc C20H35NO15 FW 529.49 [71208-06-5]
EOT-GLY050	Lewis^X抗原四糖 (Le^X) Lewis^X (Le^X) tetraose			Galβ1-4(Fucα1-3)GlcNAcβ1-3Gal C26H45NO20 FW 691.62
EOT-GLY051	Lewis^X (抗原六糖 (Le^X) Lewis^X (Le^X)hexaose Lacto-N-neodifucohexaose (LNnDFH)			Galβ1-4GlcNAc C14H25NO11 FW 383.35 [32181-59-2]
	Human Milk Oligosaccharide Kunz et al., 2000. Ann Rev Nutr. 20, 699-722 Product provided for the following study : “Structural basis for the interaction between human milk oligosaccharide and the bacterial lectin PA-IIL of Pseudomonas aeruginosa” Perret S et al., 2005. Biochem J. Jul 15;389.
EOT-GLY048	Lewis^Y抗原四糖 (Le^Y) Lewis^Y (Le^Y) tetraose			Fucα1-2Galβ1-4(Fucα1-3)GlcNAc C26H45NO19 FW 675.63 [82993-43-9]
EOT-GLY052	Lewis^Y抗原五糖 (Le^Y) Lewis^Y (Le^Y) pentaose			Fucα1-2Galβ1-4(Fucα1-3)GlcNAcβ1-3Gal C32H55NO24 FW 837.77
EOT-GLY046	Lewis^a抗原三糖 (Le^a) Lewis^a (Le^a) triaose			Galβ1-3(Fucα1-4)GlcNAc C20H35NO15 FW 529.49 [56570-03-7]
EOT-GLY054	Lewis^a抗原四糖 (Le^a) Lewis^a (Le^a)tetraose			Galβ1-3(Fucα1-4)GlcNAcβ1-3Gal C26H45NO20 FW 837.77
EOT-GLY055	Lewis^a抗原六糖 (Le^a) Lewis^a (Le^a) hexaose Lacto-N-difucohexaose II (LNDFH II)			Galβ1-3(Fucα1-4)GlcNAcβ1-3Galβ1-4(Fucα1-3)Glc C38H65NO29 FW 999.90 [62258-12-2]
	Human Milk Oligosaccharide Kunz et al., 2000. Ann Rev Nutr. 20, 699-722
EOT-GLY045	Lewis^b抗原四糖 (Le^b) Lewis^b (Le^b) tetraose			Fucα1-2Galβ1-3(Fucα1-4)GlcNAc C26H45NO19 FW 675.63 [80081-06-7]
EOT-GLY056	Lewis^b抗原五糖 (Le^b) Lewis^b (Le^b) pentaose			Fucα1-2Galβ1-3(Fucα1-4)GlcNAcβ1-3Gal C32H55NO24 FW 837.77
	Receptor of gastric pathogenic strain Becker DJ, Lowe JB. 2003. Glycobiology. Jul; 13(7): 41R- 53R
EOT-GLY047	唾液酸 Lewis^X抗原四糖 (SLe^X) Sialyl Lewis^X (sLe^X) tetraose			Neu5Acα2-3Galβ1-4(Fucα1-3)GlcNAc C31H51N2O23Na FW 842.72 [98603-84-0]

EOT-GLY053	唾液酸 Lewis^X抗原五糖 (SLe^X) Sialyl Lewis^X (sLe^X) pentaose			Neu5Acα2-3Galβ1-4(Fucα1-3)GlcNAcβ1-3Gal C37H61N2O28Na FW 1004.86
	Ligand of selectin-dependent leukocyte adhesion Berg EL et al,. 1991. J Biol Chem. 266(23):14869-72 Tumor-associated-antigen (TACA) Magnani JL. 1991. Glycobiology. Sep;1(4):318-20
EOT-GLY044	唾液酸 Lewis^a抗原四糖 (SLe^a) Sialyl Lewis^a (sLe^a) tetraose			Neu5Acα2-3Galβ1-3(Fucα1-4)GlcNAc C31H51N2O23Na FW 842.73 [92448-22-1]